The effects of hydroxyethyl starch and gelatine on lung tissue and coagulation during the resuscitation of rats with traumatic haemorrhagic shock
Yazarlar (7)
Ayten Saraçoğlu
Marmara Üniversitesi, Türkiye
Marmara Üniversitesi, Türkiye
Kemal Tolga Saraçoğlu
Sağlık Bilimleri Üniversitesi, Türkiye
Sağlık Bilimleri Üniversitesi, Türkiye
Dr. Öğr. Üyesi İlyas Samet Ergün Bezm-İ Âlem Vakıf Üniversitesi, Türkiye
Prof. Dr. Mehmet Yıldırım Sağlık Bilimleri Üniversitesi, Türkiye
Dr. Öğr. Üyesi Metehan AKÇA Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Cumaali Demirtaş
Şermin Tetik
Uluslararası Final Üniversitesi, Türkiye
Uluslararası Final Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (ESCI dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | ANAESTHESIOLOGY INTENSIVE THERAPY | ||
| Dergi ISSN | 1642-5758 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | ESCI (Emerging Sources Citation Index) | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2022 |
| Cilt / Sayı / Sayfa | 54 / 5 / 393–401 | DOI | 10.5114/ait.2022.121519 |
| Makale Linki | http://dx.doi.org/10.5114/ait.2022.121519 | ||
| UAK Araştırma Alanları |
Fizyoloji
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| Özet |
| ResultsIn the control group, R (16.18±2.74) and K (5.8±1.1) were significantly higher than in all other groups (P= 0.001), and the TEG alpha angle was 39.54±5.94, which was found to be significantly lower than in the sham group (P= 0.001). In group V, the TEG MA value was found to be significantly lower at 30.54±8.89 (P= 0.001). The annexin A5 value was significantly higher in the control group, group V, and group G than in the sham group and was highest in the control group (P= 0.001). Lung damage score measurement was 0.60±0.19 in the control group, higher than in the gelatine and HES groups (P= 0.001).ConclusionsLung tissue damage and coagulation were positively affected by HES or gelatine resuscitation. A reduction in clot formation in the HES group might be observed due to the possible negative effect on platelets. Therefore, we concluded that the use of gelatine might be advantageous until blood transfusion is initiated in traumatic haemorrhagic shock. |
| Anahtar Kelimeler |
| haemorrhage | haemorrhagic shock | rat model | trauma | coagulopathy |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |
| Google Scholar | 2 |