Comparison of focally induced epileptiform activities in C57BL/6 and BALB/c mice by using in vivo EEG recording
Yazarlar (5)
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | NEUROSCIENCE LETTERS | ||
| Dergi ISSN | 0304-3940 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2011 |
| Cilt / Sayı / Sayfa | 504 / 2 / 165–169 | DOI | 10.1016/j.neulet.2011.09.030 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0304394011013152 | ||
| UAK Araştırma Alanları |
Fizyoloji
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| Özet |
| Epilepsy characterized by repeated seizures is influenced by genetic factors. Seizure response of inbred mouse strains changes depending on the variety of stimuli including chemical (e.g., pentylenetetrazole, nicotine, cocaine, NMDA, kainate), physical (e.g., auditory) or electrical. In this study, we compared the susceptibilities of C57BL/6 and BALB/c mice strains to penicillin induced epileptiform activity (a focally induced, experimental epilepsy model), by analyzing the spike onset latency, spike amplitude and spike frequency. The power spectrums of baseline EEGs were also investigated. We found no alterations of spike onset latencies between the C57 and BALB mice. However, spike amplitudes and spike frequencies were found to be higher in BALB mice than C57 mice. With regard to EEG power spectrum, absolute power of investigated bands was not different between the two strains. Interestingly, the relative … |
| Anahtar Kelimeler |
| Penicillin induced epilepsy | C57BL/6 | BALB/c | EEG | Mice |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 13 |
| Google Scholar | 21 |