Cherry stem phenolic compounds: Optimization of extraction conditions and in vitro evaluations of antioxidant, antimicrobial, antidiabetic, anti-inflammatory, and cytotoxic activities
Yazarlar (4)
Doç. Dr. Tugba Demir Cumhuriyet Üniversitesi, Türkiye
Prof. Dr. Özlem AKPINAR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Haki Kara Cumhuriyet Üniversitesi, Türkiye
Prof. Dr. Huseyin Gungor Cumhuriyet Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (ESCI dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Food Processing and Preservation | ||
| Dergi ISSN | 0145-8892 Wos Dergi Scopus Dergi | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2020 |
| Cilt / Sayı / Sayfa | 44 / 10 / – | DOI | 10.1111/jfpp.14804 |
| Makale Linki | https://onlinelibrary.wiley.com/doi/abs/10.1111/jfpp.14804 | ||
| UAK Araştırma Alanları |
Gıda Kimyası
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| Özet |
| The present study reported the optimization of extraction of phenolic and flavonoid compounds from the cherry stem and biological activities of the extract. The extraction parameters were optimized employing a response surface methodology, and they were determined as 79°C, 35% (vol/vol) of ethanol percentage and 119 min. It was found that the extract obtained at the optimum conditions contained high amounts of sinapic acid and quercetin followed by caffeic and ferulic acid. It had a high antioxidant capacity and showed antimicrobial activities against Escherichia coli, Enterococcus fecalis, Staphylococcus aureus, Aspergillus flavus, and Aspergillus niger. The extract inhibited α‐amylase, α‐glucosidase, lipoxygenase, and xanthine oxidase enzymes which indicated that the extract had antidiabetic and anti‐inflammatory effects. It also showed cytotoxic activities on the breast and bone cancer cells. The results … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 10 |
| Scopus | 12 |
| Google Scholar | 24 |