Neutrophil Percentage-to-Albumin Ratio as a Novel Predictor of Diuretic Resistance and Mortality in Patients with Heart Failure with Preserved Ejection Fraction
Yazarlar (4)
Sefa Erdi Ömür
Doç. Dr. Kayıhan KARAMAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Çağrı Zorlu
Gülşen Genç Tapar Tokat Gaziosmanpaşa Üniversitesi
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | The Anatolian Journal of Cardiology (Q3) | ||
| Dergi ISSN | 2149-2263 Dergi Bilgileri (2026) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2026 |
| Cilt / Sayı / Sayfa | 30 / 3 / 174–183 | DOI | 10.14744/AnatolJCardiol.2026.5893 |
| Makale Linki | https://doi.org/10.14744/anatoljcardiol.2026.5893 | ||
| UAK Araştırma Alanları |
Kardiyoloji
|
||
| Özet |
| Background Heart failure with preserved ejection fraction (HFpEF) is increasingly recognized as a systemic inflammatory and metabolic disorder. Diuretic resistance remains a major therapeutic challenge in this population. The neutrophil percentage-to-albumin ratio (NPAR), a novel marker of systemic inflammation, may serve as a predictor of diuretic resistance and adverse outcomes in HFpEF. Methods This retrospective cohort study included 1 487 HFpEF patients treated between January 2017 and August 2022. Patients were divided into 2 groups: those with and without diuretic resistance. Clinical, laboratory, and echocardiographic parameters were compared between groups. Receiver-operating characteristic (ROC) analysis, logistic regression, and Kaplan–Meier survival analyses were used to determine predictive and prognostic factors. Results Patients with diuretic resistance exhibited significantly higher … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 3 |