'Surfactant-free'stable nanoparticles from biodegradable and amphiphilic poly (ε-caprolactone)-grafted dextran copolymers
Yazarlar (6)
Isabelle Ydens
Philippe Degée
Cécile Nouvel
Edith Dellacherie
Doç. Dr. Mustafa Numan BAKIRCI Türkiye
Philippe Dubois Tokat Gaziosmanpaşa Üniversitesi
| Makale Türü |
Özgün Makale
(Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale)
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| Dergi Adı | e-Polymers | ||
| Makale Dili | – | Basım Tarihi | 07-2005 |
| Makale Linki | https://pure.unamur.be/ws/files/40322679/2005_DegeeDubois_article.pdf | ||
| UAK Araştırma Alanları |
Yüksek Enerji ve Parçacık Fiziği
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| Özet |
| A variety of poly (ε-caprolactone)-grafted dextran copolymers were synthesized with a controlled architecture through a three-step procedure: partial protection of the dextran hydroxyl groups by silylation, ring-opening polymerization of ε-caprolactone initiated from remaining free hydroxyl groups on partially silylated dextran, and silyl ether deprotection under mild conditions. The potential of these amphiphilic grafted copolymers as surfactants was investigated by water/toluene interfacial tension measurements. Since each copolymer showed noticeable surfactant properties, their ability to form ‘surfactant-free’nanoparticles was evaluated using the nanoprecipitation method. It was found that remarkably stable core (polyester)-shell (polysaccharide) nanoparticles with a mean diameter around 200 nm were formed. |
| Anahtar Kelimeler |
