A pilot study assessing the association between paraoxonase 1 gene polymorphism and prostate cancer
Yazarlar (5)
Prof. Dr. Nihat ULUOCAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Doğan ATILĞAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Bekir Süha PARLAKTAŞ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Fikret ERDEMİR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Hacı Ömer ATEŞ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (ESCI dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Türk Üroloji Dergisi/Turkish Journal of Urology | ||
| Dergi ISSN | 2149-3235 | ||
| Dergi Tarandığı Indeksler | ESCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 08-2017 |
| Cilt / Sayı / Sayfa | 43 / 3 / 279–283 | DOI | 10.5152/tud.2017.74151 |
| Makale Linki | http://turkishjournalofurology.com/eng/makale/3086/167/Full-Text | ||
| UAK Araştırma Alanları |
Üroloji
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| Özet |
| Objective We aimed to show the relationship between paraoxonase 1 (PON1) gene polymorphism and the development of prostate cancer (PCa). Material and methods We investigated the association of single nuclotide polymorphisms of PON1 enzyme with the development of PCa risk. A total of 147 male patients were divided into PCa, and control groups. The control group was also divided into two subgroups according to serum prostate specific antigen (PSA) levels as non PCa-high PSA (>4 ng/mL) and non PCa-low PSA (≤4 ng/mL) groups. Results The mean ages of the patients were 64.81 years, 63.27 years and 64.22 years in PCa group, non PCa-low PSA and non PCa –high PSA groups, respectively. The mean PSA levels were 10.9 ng/mL, 1.16 ng/mL and 6.63 ng/mL for PCa group, non PCa –low PSA and non PCa –high PSA groups, respectively. In terms of PON1 polymorphisms and allele frequencies … |
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BM Sürdürülebilir Kalkınma Amaçları
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| Web of Science | 4 |
| Scopus | 4 |
| Google Scholar | 6 |