Relationship between vascular endothelial growth factor gene polymorphisms and Crimean-Congo hemorrhagic fever
Yazarlar (6)
Prof. Dr. Umut Safiye ŞAY COŞKUN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Recai Aci Türkiye
Dr. Öğr. Üyesi Nihan BOZKURT Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Rev Assoc Med Bras (Q2)
Dergi ISSN 1806-9282 Dergi Bilgileri (2025)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 08-2025
Cilt / Sayı / Sayfa 71 / 7 / – DOI 10.1590/1806-9282.20250147
Makale Linki https://pubmed.ncbi.nlm.nih.gov/40802416/
UAK Araştırma Alanları
Tıbbi Biyoloji
Özet
SUMMARY OBJECTIVE: This study aims to investigate the relationship between vascular endothelial growth factor gene polymorphisms and Crimean–Congo hemorrhagic fever METHODS: A total of 130 serum samples were analyzed, including 60 patients diagnosed with Crimean–Congo hemorrhagic fever and 70 healthy controls. Genetic analyses were performed using polymerase chain reaction and restriction fragment length polymorphism techniques. RESULTS: Significant differences were observed between patient and control groups in terms of vascular endothelial growth factor −460 C/T and -ID (18 bp) polymorphisms. CONCLUSION: Vascular endothelial growth factor gene polymorphisms may contribute to genetic susceptibility to Crimean–Congo hemorrhagic fever. Further studies with larger sample sizes are recommended to support these findings.
Anahtar Kelimeler
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
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PubMed 1
Relationship between vascular endothelial growth factor gene polymorphisms and Crimean-Congo hemorrhagic fever