Potential regulation of certain genes at the transcription level for ferroptosis evasion in triple-negative breast cancer (TNBC): A hypothesis
Yazarlar (1)
Dr. Öğr. Üyesi Çağlar BERKEL
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
| Makale Alt Türü | SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
| Dergi Adı | Medical Hypotheses |
| Dergi ISSN | 0306-9877 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2024 |
| Cilt No | 189 |
| Sayı | 1 |
| DOI Numarası | 10.1016/j.mehy.2024.111413 |
| Özet |
| Ferroptosis is an iron-dependent cell death mechanism, caused by iron accumulation-mediated generation of lipid peroxidation, distinct from other forms of cell death such as pyroptosis [1],[2]. Various mechanisms of ferroptosis evasion exist in tumors. In recent years, many proteins have been identified to influence the vulnerability of breast cancer cells to ferroptotic cell death [3],[4],[5],[6],[7],[8],[9],[10],[11]. Some of these proteins suppress ferroptosis and are associated with ferroptosis resistance/evasion, whereas others promote ferroptosis and increase sensitivity to ferroptotic cell death in breast cancer. Here, those proteins reported in papers published very recently (in 2024) were particularly taken into account. It was found that five proteins which were shown to be associated with ferroptosis inhibition in breast cancer (namely, LAMC2, LPCAT1, POU2F2, SRSF1 and TFAP2C)[3],[4],[5],[6],[7] have higher mRNA ... |
| Anahtar Kelimeler |
Science Direct
Potential regulation of certain genes at the transcription level for ferroptosis evasion in triple-negative breast cancer (TNBC): A hypothesis
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| Atıf Sayıları | |
| WoS | 1 |
| SCOPUS | 1 |
| Google Scholar | 1 |