Potentiometric urea biosensors        
Yazarlar (4)
Doç. Dr. Oğuz ÖZBEK Zonguldak Bülent Ecevit Üniversitesi, Türkiye
Dr. Öğr. Üyesi Çağlar BERKEL Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ömer IŞILDAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
İbrahim Işıldak
Yıldız Teknik Üniversitesi, Türkiye
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı Clinica Chimica Acta
Dergi ISSN 0009-8981 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q1
Makale Dili İngilizce
Basım Tarihi 01-2022
Cilt No 524
Sayı 1
Sayfalar 154 / 163
DOI Numarası 10.1016/j.cca.2021.11.011
Makale Linki https://www.sciencedirect.com/science/article/abs/pii/S0009898121003946
Özet
Excess nitrogen in the body is converted to urea in the liver, and urea is disposed as a waste product in urine. Urea concentration can change in body fluids such as blood due to the presence of certain disorders. Therefore, the determination of urea is of high importance in various areas including medical diagnosis, as well as food quality control and environmental monitoring. Potentiometric sensors have certain advantages over their alternatives, such as rapidity, portability, cost effectiveness, high sensitivity, easy operation and simple apparatus. Potentiometric urea biosensors based on enzyme urease have been developed using various materials including nanoparticles and films, and also using different methodologies. In this review, we covered potentiometric urea biosensors reported in the literature, and touched upon their certain structure characteristics and performance parameters including detection limit, working concentration range, response time and lifetime, all of which are of practical importance. Each potentiometric urea biosensor has its own advantages and drawbacks, thus the selection of appropriate method depends on the sample to be analyzed, its urea concentration range and other requirements of the particular application. Further research is needed in order to optimize the performance of these devices and to broaden their applicability.
Anahtar Kelimeler
Biomedical analysis | Biosensor | Clinical chemistry | Medical diagnosis | Potentiometry | Urea
Science Direct
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 38
SCOPUS 51
Google Scholar 66
Potentiometric urea biosensors

Paylaş