The Photolyase/Cryptochrome Family of Proteins as DNA Repair Enzymes and Transcriptional Repressors
Yazarlar (11)
Koç Üniversitesi, Türkiye
Koç Üniversitesi, Türkiye
Koç University, Türkiye
Koç University, Türkiye
Koç University, Türkiye
Koç University, Türkiye
Koç University, Türkiye
Koç University, Türkiye
Dr. Öğr. Üyesi Çağlar BERKEL
Koç University, Türkiye
Koç University, Türkiye
İstanbul Medeniyet Üniversitesi, Türkiye
| Makale Türü |
Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği,
araştırma notu, bilirkişi raporu ve benzeri)
|
| Makale Alt Türü | SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
| Dergi Adı | Photochemistry and Photobiology |
| Dergi ISSN | 0031-8655 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2017 |
| Cilt No | 93 |
| Sayı | 1 |
| Sayfalar | 93 / 103 |
| DOI Numarası | 10.1111/php.12669 |
| Makale Linki | https://www.ncbi.nlm.nih.gov/pubmed/28067410 |
| Özet |
| Light is a very important environmental factor that governs many cellular responses in organisms. As a consequence, organisms possess different kinds of light-sensing photoreceptors to regulate their physiological variables and adapt to a given habitat. The cryptochrome/photolyase family (CPF) includes photoreceptors that perform different functions in different organisms. Photolyases repair ultraviolet-induced DNA damage by a process known as photoreactivation using photons absorbed from the blue end of the light spectrum. On the other hand, cryptochromes act as blue light circadian photoreceptors in plants and Drosophila to regulate growth and development. In mammals, cryptochromes have light-independent functions and are very important transcriptional regulators that act at the molecular level as negative transcriptional regulators of the circadian clock. In this review, we highlight current knowledge concerning the structural and functional relationships of CPF members. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 69 |
| SCOPUS | 73 |
| Google Scholar | 106 |