Red cell distribution width is correlated with extensive coronary artery disease in patients with diabetes mellitus
Yazarlar (8)
Prof. Dr. Ataç ÇELİK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Metin KARAYAKALI Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Fatih Altunkaş
Türkiye
Doç. Dr. Kayıhan KARAMAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Arif Arısoy
Gaziosmanpaşa Üniversitesi, Türkiye
Köksal Ceyhan
Türkiye
Hasan Kadı
Balıkesir Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı CARDIOVASCULAR JOURNAL OF AFRICA (Q4)
Dergi ISSN 1995-1892 Dergi Bilgileri (2017)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 09-2017
Cilt / Sayı / Sayfa 28 / 5 / 319–323 DOI 10.5830/CVJA-2017-015
Makale Linki https://pmc.ncbi.nlm.nih.gov/articles/PMC5730728/pdf/cvja-28-319.pdf
UAK Araştırma Alanları
Kardiyoloji
Özet
Previous studies have predicted an independent relationship between red cell distribution width (RDW) and the risk of death and cardiovascular events in patients with coronary artery disease (CAD). The aim of this study was to investigate the relationship between RDW and extensiveness of CAD in patients with diabetes mellitus (DM). Two hundred and thirty-three diabetic patients who underwent coronary angiographies at our centre in 2010 were included in the study. All of the angiograms were re-evaluated and Gensini scores were calculated. Triple-vessel disease was diagnosed in the presence of stenosis > 50% in all three coronary artery systems. RDW was significantly higher in diabetic CAD patients (p < 0.001). Patients with CAD who had a RDW value above the cut-off point also had higher Gensini scores, higher percentages of obstructive CAD and triple-vessel disease (p ≤ 0.001 for all). According to the cut-off values calculated using ROC analysis, RDW > 13.25% had a high diagnostic accuracy for predicting CAD. RDW was also positively correlated with Gensini score, obstructive CAD and triple-vessel disease (r < 0.468 and p < 0.001 for all). RDW values were found to be increased in the diabetic CAD population. Higher RDW values were related to more extensive and complex coronary lesions in patients with DM.
Anahtar Kelimeler
red cell distribution width | coronary artery disease | diabetes mellitus | Gensini score