Evaluation of Neonatal Brain Parenchyma Using 2‐Dimensional Shear Wave Elastography
Yazarlar (2)
Prof. Dr. Eda ALBAYRAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Tuba KASAP Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı JOURNAL OF ULTRASOUND IN MEDICINE (Q2)
Dergi ISSN 0278-4297 Dergi Bilgileri (2017)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 08-2017
Cilt / Sayı / Sayfa 37 / 0 / – DOI 10.1002/jum.14366
Makale Linki http://dx.doi.org/10.1002/jum.14366
UAK Araştırma Alanları
Çocuk Sağlığı ve Hastalıkları (Çocuk Sağlığı ve Hastalıkları)
Özet

Objectives

The aim of this study was to evaluate the stiffness of the neonatal brain using 2-dimensional shear wave elastography in term and preterm neonates and to investigate possible stiffness differences between groups.

Methods

A total of 83 neonates, including 44 term and 39 preterm, were included in the study. Shear wave elastographic measurements of the thalamus and occipital periventricular white matter were conducted via the anterior fontanel. The Pearson correlation coefficient was used to determine the association between the birth week and stiffness values of the thalamus and periventricular white matter. A receiver operating characteristic analysis was applied to determine the power of the stiffness of the thalamus and periventricular white matter in predicting a significant preterm classification. P < .05 was considered significant.

Results

The brain parenchymal stiffness values measured from both the thalamus and periventricular white matter were found to be significantly lower in the preterm group compared with the term group. The periventricular white matter stiffness values were found to be lower than thalamus stiffness values in both groups. According to the receiver operating characteristic curve, the optimal cutoff values for determining prematurity were defined to be less than 8.28 kPa for the mean thalamus stiffness and less than 6.59 kPa for the periventricular white matter.

Conclusions

This study shows that differences between brain stiffness values in preterm and term neonates can be shown by using 2-dimensional shear wave elastography, and the results may be reference points for evaluating neonatal brain stiffness in research on patients with various illnesses.
Anahtar Kelimeler
brain development | elastography | head and neck | neonatal | pediatrics | shear wave elastography
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Yöksis 28
PubMed 14
Evaluation of Neonatal Brain Parenchyma Using 2‐Dimensional Shear Wave Elastography