The effect of pentoxifylline on penile cavernosal tissues in ischemic priapism-induced rat model
Yazarlar (7)
Prof. Dr. Fikret ERDEMİR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Fatih Fırat Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Fatma Markoç
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Doğan ATILĞAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Bekir Süha PARLAKTAŞ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Öğr. Gör. Yunus Emre KUYUCU Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Yusuf Gencten
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | International Urology and Nephrology (Q4) | ||
| Dergi ISSN | 0301-1623 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2014 |
| Cilt / Sayı / Sayfa | 46 / 10 / 1961–1967 | DOI | 10.1007/s11255-014-0769-z |
| Özet |
| Introduction Priapism is defined as persisting (>4 h), painful and abnormal tumescence that can occur without sexual stimulation. Three subtypes priapisms are seen—the non-ischemic priapism, intermittent and the ischemic priapism. In ischemic priapism, there is an abnormality in the veno-occlusive mechanism, resulting in venous stasis and accumulation of deoxygenated blood within the penile cavernosal tissue. Cavernosal tissue necrosis develops after extended period of ischemia and is eventually replaced by fibrotic tissue. It may results in erectile dysfunction if not treated promptly. Although, standard treatment of the ischemic priapism is penile aspiration and intracavernosal alpha-adrenergic agents, new oral agents have been investigated to reduce the cavernosal damage. In this study, the effect of different doses of pentoxifylline on cavernosal tissues was evaluated.Materials and methodsThirty-six male … |
| Anahtar Kelimeler |
| Ischemia | Penis | Pentoxifylline | Priapism | Treatment |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 18 |
| Scopus | 3 |
| Web of Science | 11 |