The Relationship between ALA16VAL Single Gene Polymorphism and Renal Cell Carcinoma
    
Yazarlar (7)
Prof. Dr. Doğan ATILĞAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Bekir S. Parlaktas
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Nihat ULUOCAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Engin KÖLÜKÇÜ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Fikret ERDEMİR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Huseyin Ozyurt
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Unal Erkorkmaz Sakarya Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale)
Dergi Adı Advances in Urology
Dergi ISSN 1687-6369 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler Scopus
Makale Dili İngilizce Basım Tarihi 01-2014
Cilt / Sayı / Sayfa 2014 / 1 / 932481–0 DOI 10.1155/2014/932481
Makale Linki https://downloads.hindawi.com/journals/au/2014/932481.pdf
Özet
Objectives. The aim of this study was to investigate the association of RCC and Ala16Val polymorphism in Turkish patients with RCC. Materials and Methods. A total of 41 patients with RCC who underwent radical or partial nephrectomy in our clinic and 50 healthy volunteers living in the same geographic area were included in this study. DNA samples from serum of RCC patients and controls were genotyped for MnSOD polymorphism analysis. Genotype ratios and allele frequencies were compared between two groups and odd ratios with 95% confidence intervals were calculated statistically. A P value of <0.05 was considered statistically significant. Results. There was a significant difference in the MnSOD genotype distributions between the RCC patients and the controls in terms of Ala/Ala+Ala/Val and Val/Val genotypes (P = 0.039). The Ala/Ala+Ala/Val genotypes were found significantly suspicious for RCC with …
Anahtar Kelimeler
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Google Scholar 20
Web of Science 15
The Relationship between ALA16VAL Single Gene Polymorphism and Renal Cell Carcinoma

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