Effects of melatonin on partial unilateral ureteral obstruction induced oxidativeinjury in rat kidney
Yazarlar (7)
Prof. Dr. Doğan ATILĞAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Bekir S. Parlaktas
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Nihat ULUOCAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Fikret ERDEMİR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Fatih FIRAT Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Unal Erkorkmaz Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Oguzhan Saylan
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale)
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| Dergi Adı | Urology Annals | ||
| Dergi ISSN | 0974-7796 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | index copernicus | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2012 |
| Cilt / Sayı / Sayfa | 4 / 2 / 89–93 | DOI | 10.4103/0974-7796.95552 |
| Makale Linki | https://doi.org/10.4103/0974-7796.95552 | ||
| Özet |
| Aim:This experimental study was designed to produce ischemia-reperfusion injury in rat kidney by performing partial unilateral ureteral obstruction (PUUO) and investigated the effects of melatonin on the levels of oxidative injury parameters.Materials and Methods:Twenty-four adult male rats were randomly divided into three groups as follows; control group (Group 1); only nephrectomy and blood (5 ml) drawn from vena cava inferior, PUUO group (Group 2); PUUO (10 days)+ ipsilateral nephrectomy after recovery of PUUO+ blood from vena cava inferior VCI, melatonin treated group (Group 3); PUUO (10 days)+ melatonin (1/2 hr before release, 50 mg/kg, ip)+ ipsilateral nephrectomy after recovery of PUUO+ blood from VCI. The left ureter was embedded into the psoas muscle to create PUUO. After 10 days, PUUO was recovered and ipsilateral nephrectomies were performed for biochemical analysis of superoxide … |
| Anahtar Kelimeler |
| Kidney | melatonin | obstruction | oxidative stress | ureter |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 29 |
| Scopus | 2 |
| Web of Science | 20 |